Research

We have several ongoing and soon to start research programs. Below are the minimal details.  

Ongoing Research Support


                                                          Taylor (PI)                      09/01/2019-08/31/2022
University of Arizona                                                      
In-Person, Telehealth or Internet Cognitive-Behavioral Therapy for Insomnia (CBTi): Impacts on sleep, mental and physical health outcomes in middle aged (50-65) adults.
The overall objective of this research is to determine the relative efficacy of three different CBTi intervention modalities on improving sleep, mental and physical health outcomes in middle-aged (45-65 years old) adults with insomnia.
Role: Co-I 
Click here if interested.

R44AG056250-03A1                        Gartenberg (PI)                      06/01/2020-05/31/2022
Proactive Life, Inc (Sub-NIH/NIA SBIR)                                                      
A non-pharmacological multi-modal therapy to improve sleep and cognition and reduce mild cognitive impairment risk
The overall objective of this research is to develop a non-pharmacological means to address sleep deficiencies and well-being in older adults.
Role: Co-I

CER-2018C2-13262                      Stone/Buysse (PIs)                   05/01/2019-04/30/2023
Patient-Centered Outcomes Research Institute (PCORI)    
Cognitive Behavioral Therapy and Zolpidem for Insomnia (COZI)
Compare the effectiveness of zolpidem, CBTi, and combination treatment for insomnia symptoms over 12 months on insomnia symptoms, side effects, and other symptoms and problems, including health-related quality of life, mood, and health outcomes.
Roles: Site Co-PI; Patient Engagement Committee Member

C06OD028307                              Dake (PI)                                 09/20/2019-05/31/2024
NIH/OD
University of Arizona Health Sciences (UAHS) Sleep Research Center Construction Grant
Build a world class, state-of-the-art 8-bed sleep and circadian research center in close proximity to imaging facilities, clinical research areas, and other research laboratories within the University of Arizona campus. The center will also allow manipulation of the respired gases and administration of intravenous medications and blood sampling from an adjacent anteroom.
Role: Co-I; Executive Committee Member

No Grant ID                                     Taylor (PI)                                04/08/2020-04/07/2023
Pacific Athletic Conference – 12 (PAC-12)
The PAC-12 Student-Athlete Health and Well-Being Mental Health Coordinating Unit (MHCU)
Develop a scalable set of mental health screens, consistent with NCAA best practice recommendations, to be implemented at each PAC-12 school, facilitating policies and procedures to address positive mental health screens, and reporting on epidemiologic outcomes at the end of the study period.
Role: Primary Investigator (PI)

W81XWH-16-PRMRP-TTDA             Taylor (PI)                              12/15/2020-02/14/2022
DoD-PRMRP
Web-based provider training for cognitive behavioral therapy of insomnia (CBTi) www.CBTIweb.org
The overarching goal of this study is to develop a sophisticated, user-friendly Web-based provider training course for CBTi (CBTiWeb) which is fully sustainable and accessible with minimal cost (financial and time) to the clinician and results in knowledge gains similar to those of an in-person training.
Role: PI

R15AA026079                                     Blumenthal (PI)                      09/01/2017-08/31/2021
NIH/NIAAA    
A Controlled Test of Interpersonal Rejection, Social Anxiety, and Alcohol Use among Female Adolescents
The primary research goal is to test whether acute social stress (i.e. rejection), as compared to non-social stress, elicits greater alcohol-relevant cognitions among socially anxious girls. A secondary goal is to evaluate the indirect effects of key cognitive (i.e. disengagement coping) and psychobiological (i.e. salivary alpha amylase/cortisol ratio) variables in this relationship.
Role: Co-I

169-SR-17                                            Parthasarathy (PI)                  05/1/2019-04/14/2021
American Sleep Medicine Foundation
Non-inferiority study of telemedicine versus conventional CBTi in recently Hospitalized Patients with Insomnia
To perform comparative effectiveness research of CBTi administered by telemedicine versus conventional office-based CBTi on insomnia severity in recently hospitalized patients.
Role: Co-I

W81XWH-16-2-0004                             Brown (PI)                              09/01/2019-03/29/2021
Univ of Pennsylvania (Sub-Military Suicide Research Consortium)    
Suicide Risk and Sleep in Treatment: An Intensive Daily Sampling Study    
The primary research goal of this study is to examine whether key sleep variables are significant near-term predictors of increased suicidal ideation and the critical periods of heightened suicidal ideation. The secondary aim is to examine mediators and moderators of the associations among sleep disturbances and suicidal ideation. A final aim is to determine optimal strategies for assessing sleep and suicide risk in military personnel in treatment.
Role: Co-Investigator (Co-I)

Pending                                                  Pruiksma (PI)                         06/1/2021-05/31/2025
Peer Reviewed Medical Research Program (PRMRP)
Web-Based Provider Training for Cognitive Behavioral Therapy for Nightmares (CBT-N)
The primary aim of the proposed project is to develop a sophisticated, user friendly, web-based provider training for the evidence-based, non-pharmacological treatment, cognitive behavioral therapy for trauma-related nightmares (CBT-N), which is fully sustainable and is accessible with minimal cost (financial and time) to the clinician.
Role: Co-Investigator (Co-I)

Recent Completed Research Support

Relevant Completed Research Support (Past 3 years)
R01AI128359    Taylor (PI)    12/01/2016-11/30/2020
NIH/NIAID
Sleep and Vaccine Response in Nurses (SAV-RN)
The overarching goal of the current study is to develop a comprehensive model detailing the effects of sleep and its specific facets, as well as other risk factors, on the short-term (1-month) influenza antibody response, as well as its long-term (12-month) degradation.
Role: PI

1I01CU000144-01    Taylor (PI)    10/01/2015-09/30/2019
DoD-VA    
Treatment of Comorbid Sleep Disorders and PTSD    
The primary aim of the study was to determine if providing cognitive-behavioral therapy of insomnia and nightmares (CBTi+n) and Cognitive Processing Therapy of PTSD-Cognitive only version (CPT) results in greater PTSD and sleep symptom reduction than CPT only. The secondary aim was to determine if sequencing CBTi+n before or after CPT results in differential effects on PTSD and sleep symptom reduction.
Role: Primary Investigator
    
W81XWH-10-1-0828    Taylor (PI)    09/27/2010-9/28/2016
DoD-CDMRP    
Comparing Internet and In-Person Brief Cognitive Behavioral Therapy of Insomnia in Active Duty Military Personnel
The goal of this project was to compare in-person and internet insomnia treatments in active duty military.
Role: Primary Investigator