We have several ongoing and soon to start research programs. Below are the minimal details.
Ongoing Research
EMW-2020-FP-00200 McLean (PI) 9/8/2021-9/7/2024
An Efficient Treatment for Posttraumatic Injury for Firefighters
FEMA Role: Co-I
W81XWH-21-1-0576 Pruiksma (PI) 9/1/2021-8/31/2025
Web-Based Provider Training for Cognitive Behavioral Therapy for Nightmares (CBT-N)
DoD/CDMRP/JWMRP Role: Co-I
R01HD106413 O’Haire (PI) 09/07/2021-09/06/2026
Multi-site, longitudinal trial evaluating the efficacy, mechanisms, and moderators of service dogs for military veterans with PTSD
NIH – NICHD Role: Co-I
HT94252311080 Parsons (PI) 9/1/2023-8/31/2027
Virtual Insomnia Patients (VIPs) to Accelerate Dissemination of Precision Diagnosis and Treatment of Insomnia
DoD/Peer Reviewed Medical Research Program (PRMRP) Role: Co-I
TBD Killgore (PI) 9/01/2024-8/31/2027
Effectiveness of Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep
NIH/NIA Role: Co-I
IIR 21-005 Back (PI) 10/1/2023-9/31/2027
Development and Testing of COPEWeb: A Web-Based Provider Training for Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE)
VA Role: Co-I
R01HL162799 Haynes (PI) 8/1/2023-9/31/2028
Assessing Clinical Effectiveness and Implementation of Worksite Sleep Health Coaching in Firefighters
NIH Role: Co-I
HT9425-23-2-0014 McLean (PI) 08/31/2023-01/31/2029
Accelerated Treatment for Co-Occurring Insomnia, Nightmares, and PTSD
DoD/Peer Reviewed Medical Research Program (PRMRP) Role: Co-I
HT9425-24-1-0178 O’Haire (PI) 9/01/2024-8/31/2029
Psychiatric Service Dogs and Prolonged Exposure Therapy for Military-Connected PTSD: A Randomized Clinical Trial
DoD Role: Co-PI
Recent Completed Research Support
R44AG056250-03A1 Gartenberg (PI) 06/01/2020-05/31/2022
Proactive Life, Inc (Sub-NIH/NIA SBIR)
A non-pharmacological multi-modal therapy to improve sleep and cognition and reduce mild cognitive impairment risk
The overall objective of this research is to develop a non-pharmacological means to address sleep deficiencies and well-being in older adults.
Role: Co-I
CER-2018C2-13262 Stone/Buysse (PIs) 05/01/2019-04/30/2023
Patient-Centered Outcomes Research Institute (PCORI)
Cognitive Behavioral Therapy and Zolpidem for Insomnia (COZI)
Compare the effectiveness of zolpidem, CBTi, and combination treatment for insomnia symptoms over 12 months on insomnia symptoms, side effects, and other symptoms and problems, including health-related quality of life, mood, and health outcomes.
Roles: Site Co-PI; Patient Engagement Committee Member
C06OD028307 Dake (PI) 09/20/2019-05/31/2024
NIH/OD
University of Arizona Health Sciences (UAHS) Sleep Research Center Construction Grant
Build a world class, state-of-the-art 8-bed sleep and circadian research center in close proximity to imaging facilities, clinical research areas, and other research laboratories within the University of Arizona campus. The center will also allow manipulation of the respired gases and administration of intravenous medications and blood sampling from an adjacent anteroom.
Role: Co-I; Executive Committee Member
No Grant ID Taylor (PI) 04/08/2020-04/07/2023
Pacific Athletic Conference – 12 (PAC-12)
The PAC-12 Student-Athlete Health and Well-Being Mental Health Coordinating Unit (MHCU)
Develop a scalable set of mental health screens, consistent with NCAA best practice recommendations, to be implemented at each PAC-12 school, facilitating policies and procedures to address positive mental health screens, and reporting on epidemiologic outcomes at the end of the study period.
Role: Primary Investigator (PI)
W81XWH-16-PRMRP-TTDA Taylor (PI) 12/15/2020-02/14/2022
DoD-PRMRP
Web-based provider training for cognitive behavioral therapy of insomnia (CBTi) www.CBTIweb.org
The overarching goal of this study is to develop a sophisticated, user-friendly Web-based provider training course for CBTi (CBTiWeb) which is fully sustainable and accessible with minimal cost (financial and time) to the clinician and results in knowledge gains similar to those of an in-person training.
Role: PI
R15AA026079 Blumenthal (PI) 09/01/2017-08/31/2021
NIH/NIAAA
A Controlled Test of Interpersonal Rejection, Social Anxiety, and Alcohol Use among Female Adolescents
The primary research goal is to test whether acute social stress (i.e. rejection), as compared to non-social stress, elicits greater alcohol-relevant cognitions among socially anxious girls. A secondary goal is to evaluate the indirect effects of key cognitive (i.e. disengagement coping) and psychobiological (i.e. salivary alpha amylase/cortisol ratio) variables in this relationship.
Role: Co-I
169-SR-17 Parthasarathy (PI) 05/1/2019-04/14/2021
American Sleep Medicine Foundation
Non-inferiority study of telemedicine versus conventional CBTi in recently Hospitalized Patients with Insomnia
To perform comparative effectiveness research of CBTi administered by telemedicine versus conventional office-based CBTi on insomnia severity in recently hospitalized patients.
Role: Co-I
W81XWH-16-2-0004 Brown (PI) 09/01/2019-03/29/2021
Univ of Pennsylvania (Sub-Military Suicide Research Consortium)
Suicide Risk and Sleep in Treatment: An Intensive Daily Sampling Study
The primary research goal of this study is to examine whether key sleep variables are significant near-term predictors of increased suicidal ideation and the critical periods of heightened suicidal ideation. The secondary aim is to examine mediators and moderators of the associations among sleep disturbances and suicidal ideation. A final aim is to determine optimal strategies for assessing sleep and suicide risk in military personnel in treatment.
Role: Co-Investigator (Co-I)
Pending Pruiksma (PI) 06/1/2021-05/31/2025
Peer Reviewed Medical Research Program (PRMRP)
Web-Based Provider Training for Cognitive Behavioral Therapy for Nightmares (CBT-N)
The primary aim of the proposed project is to develop a sophisticated, user friendly, web-based provider training for the evidence-based, non-pharmacological treatment, cognitive behavioral therapy for trauma-related nightmares (CBT-N), which is fully sustainable and is accessible with minimal cost (financial and time) to the clinician.
Role: Co-Investigator (Co-I)
Relevant Completed Research Support (Past 3 years)
R01AI128359 Taylor (PI) 12/01/2016-11/30/2020
NIH/NIAID
Sleep and Vaccine Response in Nurses (SAV-RN)
The overarching goal of the current study is to develop a comprehensive model detailing the effects of sleep and its specific facets, as well as other risk factors, on the short-term (1-month) influenza antibody response, as well as its long-term (12-month) degradation.
Role: PI
1I01CU000144-01 Taylor (PI) 10/01/2015-09/30/2019
DoD-VA
Treatment of Comorbid Sleep Disorders and PTSD
The primary aim of the study was to determine if providing cognitive-behavioral therapy of insomnia and nightmares (CBTi+n) and Cognitive Processing Therapy of PTSD-Cognitive only version (CPT) results in greater PTSD and sleep symptom reduction than CPT only. The secondary aim was to determine if sequencing CBTi+n before or after CPT results in differential effects on PTSD and sleep symptom reduction.
Role: Primary Investigator
W81XWH-10-1-0828 Taylor (PI) 09/27/2010-9/28/2016
DoD-CDMRP
Comparing Internet and In-Person Brief Cognitive Behavioral Therapy of Insomnia in Active Duty Military Personnel
The goal of this project was to compare in-person and internet insomnia treatments in active duty military.
Role: Primary Investigator